Insights into host-microbe interaction: What can we do for the swine industry?

Lijuan Fan; Bingnan Liu; Ziyi Han; Wenkai Ren

doi:10.1016/j.aninu.2020.10.003

Insights into host-microbe interaction: What can we do for the swine industry?

Anim Nutr. 2021 Mar;7(1):17-23. doi: 10.1016/j.aninu.2020.10.003. Epub 2020 Dec 1.

Authors

Lijuan Fan¹, Bingnan Liu¹, Ziyi Han¹, Wenkai Ren¹

Affiliation

¹ State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangdong Laboratory of Lingnan Modern Agriculture, National Engineering Research Center for Breeding Swine Industry, Guangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou, 510642, China.

Abstract

Recent discoveries have underscored the cross-talk between intestinal microbes and their hosts. Notably, intestinal microbiota impacts the development, physiological function and social behavior of hosts. This influence usually revolves around the microbiota-gut-brain axis (MGBA). In this review, we firstly outline the impacts of the host on colonization of intestinal microorganisms, and then highlight the influence of intestinal microbiota on hosts focusing on short-chain fatty acid (SCFA) and tryptophan metabolite-mediated MGBA. We also discuss the intervention of intestinal microbial metabolism by dietary supplements, which may provide new strategies for improving the welfare and production of pigs. Overall, we summarize a state-of-the-art theory that gut microbiome affects brain functions via metabolites from dietary macronutrients.

Keywords: Gut microbiota; Microbiota-gut-brain axis; Pig; Short-chain fatty acid; Tryptophan.

Publication types

Review