The effects of substance use on severe acute respiratory syndrome coronavirus infection risks and outcomes

Curr Opin Psychiatry. 2021 Jul 1;34(4):386-392. doi: 10.1097/YCO.0000000000000711.

Abstract

Purpose of review: Severe acute respiratory syndrome coronavirus (SARS-CoV2) infection rates are currently occurring at alarmingly accelerated rates. There is also a long-standing and concurrent rise in the prevalence and severity of substance use disorders (SUD). Therefore, the intersection between these two conditions needs to be carefully considered to ensure a more effective delivery of healthcare.

Recent findings: Generally, those with SUDs are more likely to have higher risk social determinants of health factors. Therefore, these patients are more likely to have barriers that can create difficulties in following appropriate infection control measures which in turn increases the risk of exposure to SARS-CoV2. In addition, these individuals have higher rates of medical comorbidities which increases the risk of all adverse outcomes, including mortality, from SARS-CoV2 infection.

Summary: Individuals with SUDs are at increased risk of both contracting SARS-CoV2 infection and suffering from worse outcomes afterwards. Though these risks of adverse outcomes are specific of SARS-CoV2 infection, the risk of exposure to other infectious diseases is increased in this population too. Healthcare providers and policymakers should then consider how to better protect this at-risk population and alleviate this increased disease burden.

Publication types

  • Review

MeSH terms

  • COVID-19 / complications*
  • COVID-19 / pathology
  • COVID-19 / therapy*
  • Humans
  • Patient Outcome Assessment*
  • RNA, Viral
  • Risk
  • Risk Factors
  • SARS-CoV-2
  • Substance-Related Disorders / complications*
  • Substance-Related Disorders / pathology

Substances

  • RNA, Viral