[Sjögren's Syndrome]

Brain Nerve. 2021 May;73(5):552-559. doi: 10.11477/mf.1416201798.
[Article in Japanese]

Abstract

Sjögren's syndrome is an autoimmune disease characterized by chronic sialadenitis and keratoconjunctivitis sicca. While dryness of the salivary and lacrimal glands is a core symptom, neurological complications are known to occur as part of a variety of extraglandular manifestations. The reported frequency of neurological complications ranges from 1.8% to 60%, with a wide variety of central, peripheral, and muscular manifestations. In 25% of cases, neurological symptoms precede the diagnosis of Sjögren's syndrome. Therefore, in the presence of unexplained neurological symptoms, it is important to exclude Sjogren's syndrome.

MeSH terms

  • Humans
  • Sjogren's Syndrome* / diagnosis