Direct oral anticoagulants for myeloproliferative neoplasms: results from an international study on 442 patients

Tiziano Barbui; Valerio De Stefano; Alessandra Carobbio; Alessandra Iurlo; Alberto Alvarez-Larran; Beatriz Cuevas; Francisca Ferrer Marín; Alessandro M Vannucchi; Francesca Palandri; Claire Harrison; Hassan Sibai; Martin Griesshammer; Massimiliano Bonifacio; Elena M Elli; Chiara Trotti; Steffen Koschmieder; Giuseppe Carli; Giulia Benevolo; Jean-Christophe Ianotto; Swati Goel; Anna Falanga; Silvia Betti; Daniele Cattaneo; Eduardo Arellano-Rodrigo; Lara Mannelli; Nicola Vianelli; Andrew Doyle; Vikas Gupta; Kai Wille; Douglas Tremblay; John Mascarenhas

doi:10.1038/s41375-021-01279-1

Direct oral anticoagulants for myeloproliferative neoplasms: results from an international study on 442 patients

Leukemia. 2021 Oct;35(10):2989-2993. doi: 10.1038/s41375-021-01279-1. Epub 2021 May 19.

Authors

Tiziano Barbui^#¹, Valerio De Stefano^#², Alessandra Carobbio³, Alessandra Iurlo⁴, Alberto Alvarez-Larran⁵, Beatriz Cuevas⁶, Francisca Ferrer Marín⁷, Alessandro M Vannucchi⁸, Francesca Palandri⁹, Claire Harrison¹⁰, Hassan Sibai¹¹, Martin Griesshammer¹², Massimiliano Bonifacio¹³, Elena M Elli¹⁴, Chiara Trotti¹⁵, Steffen Koschmieder¹⁶, Giuseppe Carli¹⁷, Giulia Benevolo¹⁸, Jean-Christophe Ianotto¹⁹, Swati Goel²⁰, Anna Falanga^{21

22}, Silvia Betti², Daniele Cattaneo⁴, Eduardo Arellano-Rodrigo⁵, Lara Mannelli⁸, Nicola Vianelli⁹, Andrew Doyle¹⁰, Vikas Gupta¹¹, Kai Wille¹², Douglas Tremblay²³, John Mascarenhas²³

Affiliations

¹ FROM Research Foundation, ASST Papa Giovanni XXIII, Bergamo, Italy. tbarbui@fondazionefrom.it.
² Section of Hematology, Department of Radiological and Hematological Sciences, Catholic University, Policlinico Universitario "A. Gemelli" IRCCS, Roma, Italy.
³ FROM Research Foundation, ASST Papa Giovanni XXIII, Bergamo, Italy.
⁴ Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.
⁵ Hospital Clinic, Barcelona - GEMFIN, Barcelona, Spain.
⁶ Hospital de Burgos - GEMFIN, Burgos, Spain.
⁷ Hospital Morales Messeguer, Murcia - GEMFIN, Murcia, Spain.
⁸ CRIMM, Center Research and Innovation of Myeloproliferative Neoplasms, University of Florence, AOU Careggi, Firenze, Italy.
⁹ Institute of Hematology "L. & A. Seragnoli", IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
¹⁰ Guy's and St Thomas' NHS Foundation Trust, London, UK.
¹¹ Princess Margaret Cancer Centre, Toronto, ON, Canada.
¹² Johannes Wesling Medical Center, University of Bochum, Bochum, Germany.
¹³ Department of Medicine, Section of Hematology, University of Verona, Verona, Italy.
¹⁴ Hematology Division and Bone Marrow Unit, San Gerardo Hospital, ASST Monza, Monza, Italy.
¹⁵ Dipartimento di Medicina Molecolare, Università degli Studi di Pavia, Pavia, Italy.
¹⁶ Faculty of Medicine, Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, RWTH Aachen University, Aachen, Germany.
¹⁷ Ospedale San Bortolo, Vicenza, Italy.
¹⁸ Hematology, AOU Città della Salute e della Scienza di Torino, Turin, Italy.
¹⁹ Service d'Hématologie Clinique, Institut de Cancéro-Hématologie, CHRU de Brest, Brest, France.
²⁰ Albert Einstein Montefiore Medical Center, New York, NY, USA.
²¹ ASST Papa Giovanni XXIII, Bergamo, Italy.
²² School of Medicine, University of Milan Bicocca, Monza, Italy.
²³ Icahn School of Medicine at Mount Sinai, New York, NY, USA.

^# Contributed equally.

No abstract available

Publication types

Multicenter Study
Observational Study
Research Support, Non-U.S. Gov't

MeSH terms

Administration, Oral
Anticoagulants / administration & dosage*
Atrial Fibrillation / drug therapy*
Atrial Fibrillation / etiology
Atrial Fibrillation / pathology
Humans
International Agencies
Myeloproliferative Disorders / complications*
Venous Thromboembolism / drug therapy*
Venous Thromboembolism / etiology
Venous Thromboembolism / pathology

Substances

Anticoagulants