[The role of micronutrients in the comprehensive rehabilitation of patients with the novel coronavirus infection COVID-19]

Vopr Pitan. 2021;90(2):40-49. doi: 10.33029/0042-8833-2021-90-2-40-49. Epub 2021 Mar 11.
[Article in Russian]


Post-COVID disorders syndrome (PCDS) is an umbrella term for a complex of persistent symptoms that a patient can develop after suffering from COVID-19. The aim of the research was to systematize data on the role of micronutrients in the treatment of PCDS. Material and methods. The authors carried out a systematic analysis of foreign (ncbi. nlm.nih.gov) and Russian (elibrary.ru) scientific publications. Results. The most common symptoms that can persist for a long time after a coronavirus infection can be divided into 4 groups: 1) hypoxic syndrome (respiratory and oxygen deficiency); 2) asthenic syndrome; 3) syndrome of neuropsychiatric disorders; 4) gastrointestinal symptoms. Adequate dietary intake of vitamins and mineral substances is critical for the proper functioning of the immune system and maintenance of the organism functional reserves. The optimal consumption of vitamins D, C and E, zinc and ω-3 fatty acids with ration can be useful for preventing infection, supporting immunity during COVID-19 disease and in the complex of rehabilitation of patients with PCDS. Conclusion. Intake of dietary supplements containing complex of micronutrients can be recommended as a rational adjuvant therapy during the rehabilitation period after COVID-19. However, further research is essential to determine the effective dosage of vitamins and other micronutrients to reduce the manifestations of PCDS.

Keywords: COVID-19; micronutrients; mineral elements; nutritional support; post-COVID disorders syndrome; rehabilitation; vitamins.

Publication types

  • Review

MeSH terms

  • COVID-19 / rehabilitation*
  • Dietary Supplements*
  • Humans
  • Micronutrients / therapeutic use*
  • Nutritional Status*
  • SARS-CoV-2*


  • Micronutrients