Verification of the delivered patient radiation dose for non-coplanar beam therapy

J Appl Clin Med Phys. 2021 Jul;22(7):110-120. doi: 10.1002/acm2.13280. Epub 2021 May 22.

Abstract

Purpose: There is an increased interest in using non-coplanar beams for radiotherapy, including SBRT and SRS. This approach can significantly reduce doses to organs-at-risk, however, it requires stringent quality assurance, especially when a dynamic treatment couch is used. In this work, new functionality that allows using non-coplanar beam arrangements in addition to conventional coplanar beams was added and validated to the previously developed in vivo dose verification system.

Methods: The existing program code was modified to manage the additional treatment couch parameters: angle and positions. Ten non-coplanar test plans that use a static couch were created in the treatment planning system. Also, two plans that use a dynamic treatment couch were created and delivered using Varian Developer mode, since the treatment planning system does not support a dynamic couch. All non-coplanar test trajectories were delivered on a simple geometric phantom, using an Edge linear accelerator (Varian Medical Systems) with the megavoltage imager deployed and acquiring megavoltage transmission images that were used to calculate the delivered 3D dose distributions in the phantom with the updated dose calculation algorithm. The reconstructed dose distributions were compared using the 3D chi-comparison test with 2%/2mm tolerances to the corresponding reference dose distributions obtained from the treatment planning system.

Results: The chi-comparison test resulted in at least a 97.0% pass rate over the entire 3D volume for all tested trajectories. For static gantry, static couch non-coplanar fields, and non-coplanar arcs using dynamic couch the pass rates observed were at least 98%, while for the static couch, non-transverse coplanar arc fields, pass rates were at least 97%.

Conclusions: A model-based 3D dose calculation algorithm has been extended and validated for a variety of non-coplanar beam trajectories of different complexities. This system can potentially be applied for quality assurance of treatment delivery systems that use complex, non-coplanar beam arrangements.

Keywords: EPID dosimetry; QA in radiotherapy; SBRT; in vivo dosimetry; non-coplanar treatment.

MeSH terms

  • Humans
  • Particle Accelerators
  • Phantoms, Imaging
  • Radiation Dosage
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted*
  • Radiotherapy, Intensity-Modulated*