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. 2019 Nov 21;17(3):792-804.
doi: 10.5114/aoms.2019.89894. eCollection 2021.

Antioxidative activity of probiotics

Affiliations

Antioxidative activity of probiotics

Arkadiusz Hoffmann et al. Arch Med Sci. .

Abstract

Probiotics are defined as live microorganisms that have a beneficial effect on health by exhibiting quantitative and qualitative effects on intestinal microflora and/or modification of the immune system. A strain is considered probiotic if it demonstrates a series of clinically proven health benefits. In recent years, the number of studies related to the antioxidant properties of probiotics has significantly increased. Antioxidants are substances that inhibit the degree of oxidation of molecules and cause the transformation of radicals into inactive derivatives. The incorrect or inefficient antioxidant mechanisms results in oxidative stress and may occur in the course of many diseases such as diabetes, atherosclerosis, inflammatory bowel disease or damage to the heart, brain or transplanted organs. Correct functioning of antioxidant mechanisms seems to be crucial for the proper functioning of our body; therefore, probiotics should be carefully investigated for potential antioxidant properties.

Keywords: microbiota; oxidative stress; reactive oxygen species.

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Conflict of interest statement

The authors declare no conflict of interest

Figures

Figure 1
Figure 1
Mechanisms of probiotic antioxidant activity

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References

    1. Ray P, Huang B, Tsuji Y. Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling. Cell Signal. 2012;24:981–90. - PMC - PubMed
    1. Song P, Zou MH. Roles of reactive oxygen species in physiology and pathology. In: Song P, Zou MH, editors. Atherosclerosis: Risks, Mechanisms, and Therapies. John Wiley & Sons; 2015. pp. 379–92.
    1. Mateen S, Moin S, Khan AQ, Zafar A, Fatima N. Increased reactive oxygen species formation and oxidative stress in rheumatoid arthritis. PLoS One. 2016;11:e0152925. - PMC - PubMed
    1. Endres L, Begley U, Clark R, et al. Alkbh8 regulates selenocysteine-protein expression to protect against reactive oxygen species damage. PLoS One. 2015;10:e0131335. - PMC - PubMed
    1. Ito T, Kimura S, Seto K, et al. Peroxiredoxin I plays a protective role against UVA irradiation through reduction of oxidative stress. J Dermatol Sci. 2014;74:9–17. - PubMed

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