Optimal Management of Gastric Outlet Obstruction in Unresectable Malignancies

Gut Liver. 2022 Mar 15;16(2):190-197. doi: 10.5009/gnl210010.

Abstract

The aim of this article is to review the different treatment options for malignant gastric outlet obstruction (GOO) and compare their safety and efficacy. We describe the history and evolution of gastrojejunostomy (GJ), endoscopic stenting and endoscopic ultrasonography-guided gastroenterostomy (EUS-GE) and analyze the current evidence regarding these three methods available in the literature, comparing their applicability, safety, complications and cost when used for the treatment of malignant GOO. We conclude that given the benefits of endoscopic techniques and the ability to place a stent away from the tumor, EUS-GE is a promising technique that may yield an efficacy similar to that of surgical GJ and duodenal stenting, with lower reintervention rates and fewer adverse events.

Keywords: Gastric outlet obstruction; Gastroenterostomy; Palliative care; Stents; Stomach neoplasm.

Publication types

  • Review

MeSH terms

  • Endosonography
  • Gastric Bypass* / adverse effects
  • Gastric Outlet Obstruction* / etiology
  • Gastric Outlet Obstruction* / surgery
  • Gastroenterostomy / adverse effects
  • Gastroenterostomy / methods
  • Humans
  • Neoplasms* / etiology
  • Palliative Care
  • Stents / adverse effects
  • Ultrasonography, Interventional / adverse effects
  • Ultrasonography, Interventional / methods