Electric fields determine the spatial organization of microtubules and actin filaments

Med Hypotheses. 1988 Jul;26(3):165-70. doi: 10.1016/0306-9877(88)90095-3.

Abstract

A theory is proposed in which electric fields determine the spatial structure of actin filaments and microtubules in cellular processes by interacting with the dipole moments of actin and tubulin to orient these molecules in the direction of the field, thus enhancing polymerization parallel to the field lines. Applications to mitosis and chemotaxis are discussed.

MeSH terms

  • Actins*
  • Animals
  • Cytoskeleton*
  • Electricity*
  • Humans
  • Microtubules*
  • Polymers

Substances

  • Actins
  • Polymers