[Genetic predisposition to mucocutaneous fungal infections]

Abstract

Mucocutaneous fungal infections are common and usually occur in the presence of certain risk factors. However, these infections can occur in patients with no known risk factors. This indicates the presence of an underlying genetic susceptibility to fungi reflecting an innate or adaptive immune deficiency. In this review, we highlight genetic factors that predispose to mucocutaneous fungal infections specially candidiasis and dermatophytosis.

Keywords: Candidiasis; Candidose; Dematophytosis; Dermatophyties; Déficit immunitaire primitif; Fungal skin disease; Genetic predisposition; Mycose cutanée; Primary immunodeficiency; Prédisposition génétique.