Feasibility of Utilizing PREMM Score for Lynch Syndrome Identification in an Urban, Minority Patient Population
- PMID: 34053368
- PMCID: PMC8170358
- DOI: 10.1177/21501327211020973
Feasibility of Utilizing PREMM Score for Lynch Syndrome Identification in an Urban, Minority Patient Population
Erratum in
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Corrigendum to Feasibility of Utilizing PREMM Score for Lynch Syndrome Identification in an Urban, Minority Patient Population.J Prim Care Community Health. 2021 Jan-Dec;12:21501327211044904. doi: 10.1177/21501327211044904. J Prim Care Community Health. 2021. PMID: 34749566 Free PMC article. No abstract available.
Abstract
The PREMM5 model is a web-based clinical prediction algorithm that estimates the gene-specific risk of an individual carrying a Lynch syndrome germline mutation based on targeted family history questions. The objectives of our study were to determine the feasibility of screening for LS in an urban, minority patient population in a primary care setting using the PREMM5 model and characterize patient barriers associated with difficulty completing the questions. Participants were recruited from Tulane Internal Medicine primary care clinics on 9 random collection dates. Our data illustrates the difficulty patients have in recalling important details necessary to answer the PREMM questionnaire.
Keywords: access to care; community health; health promotion; prevention; primary care; underserved communities.
Conflict of interest statement
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References
-
- Sinicrope FA. Lynch syndrome-associated colorectal cancer. N Engl J Med. 2018;379:764-773. - PubMed
-
- Ligtenberg MJL, Kuiper RP, Chan TL, et al.. Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3′ exons of TACSTD1. Nat Genet. 2009;41:112-117. - PubMed
-
- Lynch HT, Snyder CL, Shaw TG, Heinen CD, Hitchins MP. Milestones of Lynch syndrome: 1895-2015. Nat Rev Cancer. 2015;15:181-194. - PubMed
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