Immunotherapy of cancer using chimeric antigen receptor-engineered T-cells has transformed the management of selected haematological malignancies, triggering intense clinical trial activity in this arena. This article summarises trial activity that has been published to date across the spectrum of haematological and solid tumour types.
Keywords: CAR T-cell; cancer; clinical trials; immunotherapy.
© The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Immunology.