Association of obesity with postacute sequelae of COVID-19

Diabetes Obes Metab. 2021 Sep;23(9):2183-2188. doi: 10.1111/dom.14454. Epub 2021 Jun 15.

Abstract

Obesity is a major risk factor for the development of severe coronavirus disease 2019 (COVID-19) infection and mortality. However, it is not known whether patients with obesity are at a greater risk of developing postacute sequelae of COVID-19 (PASC). In a median follow-up time of 8 months and counting from 30 days following a positive viral test of 2839 patients who did not require intensive care unit admission and survived the acute phase of COVID-19, 1230 (43%) patients required medical diagnostic tests, 1255 (44%) patients underwent hospital admission, and 29 (1%) patients died. Compared with patients with a normal body mass index (BMI), the risk of hospital admission was 28% and 30% higher in patients with moderate and severe obesity, respectively. The need for diagnostic tests to assess different medical problems, compared with patients with normal BMI, was 25% and 39% higher in patients with moderate and severe obesity, respectively. The findings of this study suggest that moderate and severe obesity (BMI ≥ 35 kg/m2 ) are associated with a greater risk of PASC.

Keywords: cohort study; observational study; weight control.

MeSH terms

  • Body Mass Index
  • COVID-19*
  • Hospitalization
  • Humans
  • Intensive Care Units
  • Obesity / complications
  • Obesity / epidemiology
  • Risk Factors
  • SARS-CoV-2