Post-traumatic stress disorder (PTSD) is a kind of chronic mental disorder after severe traumatic events. In this paper, the author reviewed the development of clinical and mechanism research of acupuncture and moxibustion for treating PTSD in the past 5 years. Clinical studies have shown that acupuncture could alleviate the symptoms of PTSD, and is an effective therapy for PTSD. The underlying mechanisms may include regulating neural circuit, neurotransmitters and receptors expression, signal pathway, apoptosis, immune cytokines and endocannabinoid system, et al. It could provide scientific basis of acupuncture and moxibustion for treating PTSD, and provide references for further study.
对近5年来国内外针灸治疗PTSD的临床和机制研究进行综述。临床研究显示, 针灸可有效减轻PTSD相关症状, 是治疗PTSD的有效手段。实验研究显示, 针灸治疗PTSD的作用机制可能涉及调节神经环路、神经递质与受体表达、信号传导通路、细胞凋亡、免疫细胞因子和内源性大麻素等方面。这可以为针灸治疗PTSD的临床应用提供科学依据, 为今后深入开展相关研究提供参考。.
Keywords: Acupuncture and moxibustion; Post-traumatic stress disorder; Review; stroke.