Eligibility for cervical cancer screening exit: Comparison of a national and safety net cohort

Gynecol Oncol. 2021 Aug;162(2):308-314. doi: 10.1016/j.ygyno.2021.05.035. Epub 2021 Jun 3.

Abstract

Objective: To determine eligibility for discontinuation of cervical cancer screening.

Methods: Women aged 64 with employer-sponsored insurance enrolled in a national database between 2016 and 2018, and those aged 64-66 receiving primary care at a safety net health center in 2019 were included. Patients were evaluated for screening exit eligibility by current guidelines: no evidence of cervical cancer or HIV-positive status and no evidence of cervical precancer in the past 25 years, and had evidence of either hysterectomy with removal of the cervix or evidence of fulfilling screening exit criteria, defined as two HPV screening tests or HPV plus Pap co-tests or three Pap tests within the past 10 years without evidence of an abnormal result.

Results: Of the 590,901 women in the national claims database, 131,059 (22.2%) were eligible to exit due to hysterectomy (1.6%) or negative screening (20.6%). Of the 1544 women from the safety net health center, 528 (34.2%) were eligible to exit due to hysterectomy (9.3%) or negative screening (24.9%). Most women did not have sufficient data available to fulfill exit criteria: 382,509 (64.7%) in the national database and 875 (56.7%) in the safety net hospital system. Even among women with 10 years of insurance claims data, only 41.5% qualified to discontinue screening.

Conclusions: Examining insurance claims in a national database and electronic medical records at a safety net institution led to remarkably similar findings: two thirds of women fail to qualify for screening exit. Additional steps to ensure eligibility prior to screening exit may be necessary to decrease preventable cervical cancers among women aged >65.

Clinical trial registration: N/A.

Keywords: Age 65 and older; Cervical cancer screening; Co-testing; Guidelines; HPV testing; Pap testing; Screening cessation.

MeSH terms

  • Administrative Claims, Healthcare / statistics & numerical data
  • Aged
  • Cohort Studies
  • Early Detection of Cancer / standards*
  • Early Detection of Cancer / statistics & numerical data
  • Electronic Health Records / statistics & numerical data
  • Eligibility Determination / standards*
  • Eligibility Determination / statistics & numerical data
  • Female
  • Humans
  • Hysterectomy / statistics & numerical data
  • Insurance Coverage / standards
  • Insurance Coverage / statistics & numerical data
  • Middle Aged
  • Papanicolaou Test / statistics & numerical data
  • Papillomavirus Infections / diagnosis*
  • Papillomavirus Infections / pathology
  • Papillomavirus Infections / virology
  • Practice Guidelines as Topic
  • Safety-net Providers / standards
  • Safety-net Providers / statistics & numerical data
  • United States
  • Uterine Cervical Neoplasms / diagnosis*
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / prevention & control
  • Uterine Cervical Neoplasms / virology
  • Vaginal Smears / statistics & numerical data