SARS-CoV-2 vaccine-induced cerebral venous thrombosis

Eur J Intern Med. 2021 Jul:89:19-21. doi: 10.1016/j.ejim.2021.05.026. Epub 2021 May 25.


The nosological entity of the cerebral venous thrombosis caused by the SARS-CoV-2 vaccination differs from the common cerebral venous thrombosis in that it is due to immune thrombocytopenia triggered by vaccination. Cerebral venous thrombosis is one of several manifestations of this type of immune thrombocytopenia. Albeit many general aspects of management of cerebral venous thrombosis are similar, immune thrombocytopenia requires a specific therapeutic approach, which is not normally adopted for cerebral venous thrombosis due to other causes, therefore its early recognition is essential.

Keywords: Adverse event; AstraZeneca vaccine; Cerebral venous thrombosis; Immune thrombocytopenia; SARS-CoV-2 vaccination; Vaccine-induced immune thrombotic thrombocytopenia; cerebral sinus thrombosis.

MeSH terms

  • COVID-19 Vaccines
  • COVID-19*
  • Humans
  • SARS-CoV-2
  • Thrombocytopenia* / chemically induced
  • Venous Thrombosis*


  • COVID-19 Vaccines