SARS-CoV-2 spike protein seropositivity from vaccination or infection does not cause sterility

F S Rep. 2021 Sep;2(3):253-255. doi: 10.1016/j.xfre.2021.05.010. Epub 2021 Jun 2.


Several reports claim that the purported similarity between syncytin-1 and the SARS-CoV-2 spike protein may induce immune cross-reactivity resulting in female sterility. We used frozen embryo transfer as a model for comparing the implantation rates between SARS-CoV-2 vaccine seropositive, infection seropositive, and seronegative women. No difference was found in serum hCG documented implantation rates or sustained implantation rates between the three groups. Reports claiming that COVID-19 vaccines or illness cause female sterility are unfounded.

Keywords: COVID-19; COVID-19 vaccination; SARS-CoV-2; implantation; spike protein; synctin-1.