Electroanatomic voltage mapping for tissue characterization beyond arrhythmia definition: A systematic review

Pacing Clin Electrophysiol. 2021 Aug;44(8):1432-1448. doi: 10.1111/pace.14288. Epub 2021 Jun 23.


Three-dimensional (3D) reconstruction by means of electroanatomic mapping (EAM) systems, allows for the understanding of the mechanism of focal or re-entrant arrhythmic circuits, which can be identified by means of dynamic (activation and propagation) and static (voltage) color-coded maps. However, besides this conventional use, EAM may offer helpful anatomical and functional information for tissue characterisation in several clinical settings. Today, data regarding electromechanical myocardial viability, scar detection in ischaemic and nonischaemic cardiomyopathy and arrhythmogenic right ventricle dysplasia (ARVC/D) definition are mostly consolidated, while emerging results are becoming available in contexts such as Brugada syndrome and cardiac resynchronisation therapy (CRT) implant procedures. As part of an invasive procedure, EAM has not yet been widely adopted as a stand-alone tool in the diagnostic path. We aim to review the data in the current literature regarding the use of 3D EAM systems beyond the definition of arrhythmia.

Keywords: imaging; new technology.

Publication types

  • Systematic Review

MeSH terms

  • Arrhythmogenic Right Ventricular Dysplasia / diagnosis
  • Brugada Syndrome / diagnosis
  • Cardiac Resynchronization Therapy Devices
  • Cardiomyopathies / diagnosis
  • Cardiovascular Diseases / diagnosis*
  • Cicatrix / diagnosis
  • Electrophysiologic Techniques, Cardiac / methods*
  • Humans
  • Imaging, Three-Dimensional
  • Myocardium / pathology