Static Versus Expandable Polyether Ether Ketone (PEEK) Interbody Cages: A Comparison of One-Year Clinical and Radiographic Outcomes for One-Level Transforaminal Lumbar Interbody Fusion

World Neurosurg. 2021 Aug:152:e492-e501. doi: 10.1016/j.wneu.2021.05.128. Epub 2021 Jun 16.

Abstract

Objective: To examine the effect of static versus expandable polyether ether ketone (PEEK) cages on both clinical and radiographic outcomes.

Methods: A retrospective cohort study was conducted on patients who underwent one-level transforaminal lumbar interbody fusion with either a static or expandable PEEK cage. Patient outcomes were obtained from chart review and radiographic outcomes were measured using standing, lateral radiographs. Recovery ratios and the proportion of patients achieving the minimally clinically important difference were calculated for Oswestry Disability Index (ODI), Physical Component Score-12, Mental Component Score-12, visual analogue scale for back, and visual analogue scale for leg at 1 year and compared between groups. Multivariate linear regression analysis was performed to determine the effect of cage type on the change in patient-reported outcome measures, controlling for demographic factors.

Results: A total of 240 patients (137 static, 103 expandable) were included in the final analysis. ΔPhysical Component Score-12 scores at 3 months were significantly greater for the static group (16.0 vs. 10.0, P = 0.043) compared with the expandable group. Multivariate regression demonstrated that use of an expandable cage was associated with greater improvements in ΔODI (β: -7.82, P = 0.048) at 1 year. No differences were found in the perioperative change in sagittal spinal alignment within or between groups at 1 year. Subsidence rates failed to show any statistically significant difference between the 2 groups.

Conclusions: Transforaminal lumbar interbody fusion with an expandable PEEK cage is an independent predictor of improved ODI scores at 1 year. Our study showed no significant differences in subsidence rates or changes in sagittal spinal alignment between static and expandable PEEK cages.

Keywords: Expandable cage; Lumbar fusion; PEEK; Patient-reported outcomes; Static cage; TLIF.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Benzophenones / chemistry*
  • Cohort Studies
  • Diffusion Chambers, Culture*
  • Disability Evaluation
  • Female
  • Humans
  • Low Back Pain / diagnostic imaging
  • Low Back Pain / surgery
  • Lumbar Vertebrae / diagnostic imaging
  • Lumbar Vertebrae / surgery*
  • Lumbosacral Region / surgery
  • Male
  • Middle Aged
  • Pain Measurement
  • Polymers / chemistry*
  • Retrospective Studies
  • Spinal Fusion / instrumentation*
  • Spine / diagnostic imaging
  • Treatment Outcome

Substances

  • Benzophenones
  • Polymers
  • polyetheretherketone