Intermediate filaments: New insights are bublin up

Meera V Sundaram

doi:10.1016/j.cub.2021.04.031

Intermediate filaments: New insights are bublin up

Curr Biol. 2021 Jun 7;31(11):R719-R721. doi: 10.1016/j.cub.2021.04.031.

Author

Meera V Sundaram¹

Affiliation

¹ Department of Genetics, University of Pennsylvania Perelman School of Medicine, Room 446a, Clinical Research Building, 415 Curie Boulevard, Philadelphia, PA 19104-6145, USA. Electronic address: sundaram@pennmedicine.upenn.edu.

PMID: 34102119
DOI: 10.1016/j.cub.2021.04.031

Abstract

Cytoplasmic intermediate filaments affect cell shape and tissue integrity, and mutations in the proteins that make up these filaments contribute to many human diseases. A new study has identified a conserved protein, BBLN-1/bublin, that is important for intermediate filament organization.

Publication types

Comment

MeSH terms

Cytoskeleton*
Humans
Intermediate Filaments*

Grants and funding

R35 GM136315/GM/NIGMS NIH HHS/United States