Aim: To evaluate the prevalence of self-directed cannabidiol (CBD) use in patients with end-stage degenerative hip and knee arthritis who underwent total hip arthroplasty and total knee arthroplasty. Materials & methods: Anonymous surveys for 109 patients were completed at 6 weeks follow-up after either total hip arthroplasty or total knee arthroplasty at a single tertiary care US orthopedic hospital. Results: Within the perioperative window encompassing both preoperative and postoperative periods, 22% (95% CI: 14-30%) of patients used CBD. Conclusion: There was no difference in pain satisfaction between patients who used CBD and patients who did not. Given high rates of self-directed perioperative CBD use and the mixed body of evidence, further research is needed to better understand whether CBD is safe and effective.
Keywords: CBD; cannabidiol; hip replacement; knee replacement.
Lay abstract Aim: To evaluate the self-guided usage rate of cannabidiol (CBD) in patients with hip and knee arthritis who underwent hip and/or knee replacement surgery. Materials & methods: Anonymous surveys for 109 patients were completed 6 weeks after either hip or knee replacement surgery at a large US orthopedic hospital. Results: Among the 109 patients who underwent hip and/or knee replacement surgery, 22% (95% CI: 14–30%) of patients used CBD. Conclusion: There was no difference in pain satisfaction between patients who used CBD and patients who did not. Given high rates of self-guided CBD use among patients undergoing hip or knee replacement surgery together with the mixed body of research, further research is needed to better understand whether CBD is safe and effective.