Association of COVID-19 mRNA Vaccine With Ipsilateral Axillary Lymph Node Reactivity on Imaging

doi:10.1001/jamaoncol.2021.1794

. 2021 Aug 1;7(8):1241-1242.

doi: 10.1001/jamaoncol.2021.1794.

Association of COVID-19 mRNA Vaccine With Ipsilateral Axillary Lymph Node Reactivity on Imaging

Mehmet Emin Adin¹, Edvin Isufi¹, Michal Kulon¹, Darko Pucar¹

Affiliations

PMID: 34110378
PMCID: PMC8193545
DOI: 10.1001/jamaoncol.2021.1794

Association of COVID-19 mRNA Vaccine With Ipsilateral Axillary Lymph Node Reactivity on Imaging

Mehmet Emin Adin et al. JAMA Oncol. 2021.

. 2021 Aug 1;7(8):1241-1242.

doi: 10.1001/jamaoncol.2021.1794.

Authors

Mehmet Emin Adin¹, Edvin Isufi¹, Michal Kulon¹, Darko Pucar¹

Affiliation

¹ Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut.

PMID: 34110378
PMCID: PMC8193545
DOI: 10.1001/jamaoncol.2021.1794

Abstract

This cohort study examines ipsilateral axillary nodal reactivity seen on positron emission tomographic and computed tomographic imaging after intramuscular administration of the coronavirus 2019 mRNA vaccines.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Kulon is an individual shareholder of pharmaceutical companies including Pfizer, Moderna, and Merck. No other conflicts are reported.

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References

1. Gallamini A, Barrington SF, Biggi A, et al. . The predictive role of interim positron emission tomography for Hodgkin lymphoma treatment outcome is confirmed using the interpretation criteria of the Deauville five-point scale. Haematologica. 2014;99(6):1107-1113. doi:10.3324/haematol.2013.103218 - DOI - PMC - PubMed
1. Coates EE, Costner PJ, Nason MC, et al. ; VRC 900 Study Team . Lymph node activation by PET/CT following vaccination with licensed vaccines for human papillomaviruses. Clin Nucl Med. 2017;42(5):329-334. doi:10.1097/RLU.0000000000001603 - DOI - PubMed
1. Shirone N, Shinkai T, Yamane T, et al. . Axillary lymph node accumulation on FDG-PET/CT after influenza vaccination. Ann Nucl Med. 2012;26(3):248-252. doi:10.1007/s12149-011-0568-x - DOI - PubMed
1. Özütemiz C, Krystosek LA, Church AL, et al. . Lymphadenopathy in COVID-19 vaccine recipients: Diagnostic dilemma in oncology patients. Radiology. 2021;210275. doi:10.1148/radiol.2021210275 - DOI - PMC - PubMed
1. CDC . Local Reactions, Systemic Reactions, Adverse Events, and Serious Adverse Events: Moderna COVID-19 Vaccine. Accessed April 7, 2021. https://www.cdc.gov/vaccines/covid-19/info-by-product/moderna/reactogeni...

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[1] Gallamini A, Barrington SF, Biggi A, et al. . The predictive role of interim positron emission tomography for Hodgkin lymphoma treatment outcome is confirmed using the interpretation criteria of the Deauville five-point scale. Haematologica. 2014;99(6):1107-1113. doi:10.3324/haematol.2013.103218 - DOI - PMC - PubMed

[2] Gallamini A, Barrington SF, Biggi A, et al. . The predictive role of interim positron emission tomography for Hodgkin lymphoma treatment outcome is confirmed using the interpretation criteria of the Deauville five-point scale. Haematologica. 2014;99(6):1107-1113. doi:10.3324/haematol.2013.103218 - DOI - PMC - PubMed

[3] Coates EE, Costner PJ, Nason MC, et al. ; VRC 900 Study Team . Lymph node activation by PET/CT following vaccination with licensed vaccines for human papillomaviruses. Clin Nucl Med. 2017;42(5):329-334. doi:10.1097/RLU.0000000000001603 - DOI - PubMed

[4] Coates EE, Costner PJ, Nason MC, et al. ; VRC 900 Study Team . Lymph node activation by PET/CT following vaccination with licensed vaccines for human papillomaviruses. Clin Nucl Med. 2017;42(5):329-334. doi:10.1097/RLU.0000000000001603 - DOI - PubMed

[5] Shirone N, Shinkai T, Yamane T, et al. . Axillary lymph node accumulation on FDG-PET/CT after influenza vaccination. Ann Nucl Med. 2012;26(3):248-252. doi:10.1007/s12149-011-0568-x - DOI - PubMed

[6] Shirone N, Shinkai T, Yamane T, et al. . Axillary lymph node accumulation on FDG-PET/CT after influenza vaccination. Ann Nucl Med. 2012;26(3):248-252. doi:10.1007/s12149-011-0568-x - DOI - PubMed

[7] Özütemiz C, Krystosek LA, Church AL, et al. . Lymphadenopathy in COVID-19 vaccine recipients: Diagnostic dilemma in oncology patients. Radiology. 2021;210275. doi:10.1148/radiol.2021210275 - DOI - PMC - PubMed

[8] Özütemiz C, Krystosek LA, Church AL, et al. . Lymphadenopathy in COVID-19 vaccine recipients: Diagnostic dilemma in oncology patients. Radiology. 2021;210275. doi:10.1148/radiol.2021210275 - DOI - PMC - PubMed

[9] CDC . Local Reactions, Systemic Reactions, Adverse Events, and Serious Adverse Events: Moderna COVID-19 Vaccine. Accessed April 7, 2021. https://www.cdc.gov/vaccines/covid-19/info-by-product/moderna/reactogeni...

[10] CDC . Local Reactions, Systemic Reactions, Adverse Events, and Serious Adverse Events: Moderna COVID-19 Vaccine. Accessed April 7, 2021. https://www.cdc.gov/vaccines/covid-19/info-by-product/moderna/reactogeni...

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Association of COVID-19 mRNA Vaccine With Ipsilateral Axillary Lymph Node Reactivity on Imaging

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Association of COVID-19 mRNA Vaccine With Ipsilateral Axillary Lymph Node Reactivity on Imaging

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Conflict of interest statement

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