Helicobacter pylori: a stealth assassin

Trends Cancer. 2021 Sep;7(9):807-808. doi: 10.1016/j.trecan.2021.05.007. Epub 2021 Jun 9.


Helicobacter pylori is a pathogen that confers the highest known risk for gastric cancer. Research directed at understanding the pathogenesis of H. pylori is crucial to identify colonized persons that may subsequently develop neoplasia. Imai et al. describe how H. pylori elicits BRCAness and endows epithelial cells with the ability to evade apoptosis.

Keywords: BRCAness; CagA; Helicobacter pylori; P53; PAR1b; gastric cancer.

Publication types

  • Comment

MeSH terms

  • Antigens, Bacterial
  • Bacterial Proteins
  • Epithelial Cells
  • Gastric Mucosa
  • Helicobacter pylori*


  • Antigens, Bacterial
  • Bacterial Proteins