Prescription Drug Monitoring Program Mandates and Opioids Dispensed Following Emergency Department Encounters for Patients With Sickle Cell Disease or Cancer With Bone Metastasis

JAMA. 2021 Jul 20;326(3):274-276. doi: 10.1001/jama.2021.10161.


This study examines the association between prescription drug monitoring program mandates and changes in opioids dispensed to patients with sickle cell disease or cancer with bone metastasis who presented to the emergency department in 29 US states.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Analgesics, Opioid / therapeutic use*
  • Anemia, Sickle Cell / complications*
  • Bone Neoplasms / complications
  • Bone Neoplasms / secondary*
  • Emergency Service, Hospital
  • Humans
  • Pain / drug therapy*
  • Pain / etiology
  • Practice Patterns, Physicians' / statistics & numerical data*
  • Prescription Drug Monitoring Programs / legislation & jurisprudence*
  • State Government
  • United States


  • Analgesics, Opioid