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. 2021 Jun 1;4(6):e2116416.
doi: 10.1001/jamanetworkopen.2021.16416.

Incidence of SARS-CoV-2 Infection in Health Care Workers After a Single Dose of mRNA-1273 Vaccine

Kalpana Gupta  1 , William J O'Brien  1 , Pamela Bellino  1 , Katherine Linsenmeyer  1 , Sucheta J Doshi  1 , Robert S Sprague  1 , Michael E Charness  1
Affiliations

Incidence of SARS-CoV-2 Infection in Health Care Workers After a Single Dose of mRNA-1273 Vaccine

Kalpana Gupta et al. JAMA Netw Open. .

Abstract

This cohort study of health care workers in a metropolitan Veterans Administration network examines the association of SARS-CoV-2 infection after receiving a single dose of mRNA-1273 vaccine compared with no vaccination.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Gupta reported ownership of equity in Moderna and Abbot Pharmaceuticals in the previous 3 years outside the submitted work. Dr Charness reported ownership of equity in Pfizer currently or in the past 3 years outside the submitted work. No other disclosures were reported.

Figures

Figure.
Figure.. Clinical Effectiveness of Dose 1 of mRNA-1273 Vaccine Against SARS-CoV-2 Infection
Hazard ratios were computed for all health care workers from day 1 (model 1), day 8 (model 2), or day 15 (model 3) after receipt of dose 1 until either day 28 (dark bars) or day 42 (light bars). Error bars indicate 95% CIs. Limiting the analysis to the period before dose 2 (28 days) did not change the outcome.
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