The leucocyte L1 protein: identity with the cystic fibrosis antigen and the calcium-binding MRP-8 and MRP-14 macrophage components

Scand J Immunol. 1988 Aug;28(2):241-5. doi: 10.1111/j.1365-3083.1988.tb02437.x.


The partial amino acid sequence of L1 protein light and heavy chains reveals an overall structure identical to the two macrophage proteins, MRP-8 and MRP-14, deduced from the sequence of the cDNA encoding the polypeptides. The light chain of L1 protein (L1-L) was shown to contain two modified amino acid residues.

MeSH terms

  • Amino Acid Sequence
  • Antigens, Surface / analysis*
  • Chemical Phenomena
  • Chemistry
  • Cystic Fibrosis / blood
  • Cystic Fibrosis / immunology
  • Humans
  • Leukocyte L1 Antigen Complex
  • Macrophages
  • Molecular Sequence Data
  • Peptide Fragments / analysis


  • Antigens, Surface
  • Leukocyte L1 Antigen Complex
  • Peptide Fragments