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. 2021 Jun 17;16(6):e0252548.
doi: 10.1371/journal.pone.0252548. eCollection 2021.

Factors influencing the iodine status of children aged 12 to 59 months from Jaffna District, Sri Lanka in the post-iodization era; a descriptive, cross-sectional study

Kandeepan Karthigesu  1 , Balakumar Sandrasegarampillai  1 , Vasanthy Arasaratnam  1
Affiliations

Factors influencing the iodine status of children aged 12 to 59 months from Jaffna District, Sri Lanka in the post-iodization era; a descriptive, cross-sectional study

Kandeepan Karthigesu et al. PLoS One. .

Abstract

Background: Iodine status, including Iodine Deficiency (ID) of the children aged 12-59 months of Jaffna District, Sri Lanka, have never been studied. This study thus aimed to assess ID among children aged 12-59 months by monitoring the Urinary Iodine Concentrations (UIC), the prevalence of goitre, and the factors causing ID.

Method: A cross-sectional study was conducted among 846 children aged 12-59 months in Jaffna District, Sri Lanka. Sociodemographic characteristics and other factors were collected using an interviewer-administered questionnaire. Dietary pattern of children was obtained using semi-quantitative food frequency questionnaire. We performed urinary iodine estimation and physical examinations to detect the goitre, according to the World Health Organization criteria. A multivariate logistic linear regression model was used to identify the factors that causing ID.

Result: The median UIC was 146.4 μg/L (interquartile range = 112.6-185.3 μg/L). Based on the UIC (<100 μg/L), 17.8% had ID, of which 15.7% and 2.1% had mild and moderate ID. The mean consumption of iodine from food was 128.7 (±20.2) μg/day. Gender variation had no influence on ID (p>0.05). Median UIC was significantly associated with living area, wealth status, type of drinking water, and method of iodized salt usage. A higher percentage of ID was significantly associated with younger age [AOR 2.32 (95% CI: 1.31-4.10)], urban area [AOR 1.94 (95% CI 1.27-2.96)], inland regions [AOR 3.20 (95% CI 1.85-5.55)], improper method of iodized salt usage [AOR 3.63 (95% CI: 1.38-9.56)], and low consumption of iodine-containing foods. The neck palpation revealed that only three children had goitre (0.4%).

Conclusion: This study revealed that high ID among the children in Jaffna children was due to improper usage of iodized salt, even though the iodized salt is freely available in the region, living area, and age, while the prevalence of goitre was not significantly identified as a public health problem.

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Conflict of interest statement

The authors have declared that no competing interests exist.

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References

    1. Bailey RL, West KP Jr., Black RE. The Epidemiology of Global Micronutrient Deficiencies. Ann Nutr Metab. 2015;66(suppl 2):22–33. doi: 10.1159/000371618 . - DOI - PubMed
    1. Andersson M, Karumbunathan V, Zimmermann MB. Global iodine status in 2011 and trends over the past decade. J Nutr. 2012;142(4):744–750. doi: 10.3945/jn.111.149393 . - DOI - PubMed
    1. Zimmermann MB, Jooste PL, Pandav CS. Iodine-deficiency disorders. Lancet 2008; 372:1251–1262. doi: 10.1016/S0140-6736(08)61005-3 . - DOI - PubMed
    1. Lazarus JH. The importance of iodine in public health. Environ Geochem Health. 2015; 37 (4):605–618. doi: 10.1007/s10653-015-9681-4 . - DOI - PubMed
    1. Biban BG, Lichiardopol C. Iodine Deficiency, Still a Global Problem? Curr Health Sci J. 2017. Api-Jun;43(2):103–111. doi: 10.12865/CHSJ.43.02.01 ; PMCID: PMC6284174. - DOI - PMC - PubMed

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Grants and funding

K.K, S.B, and V.A received the fund from National Research Council, Sri Lanka, a government organization. The principal investigator is V.A. The Grant number is NRC-13-121. The URL is https://www.nrc.gov.lk/. The funders of this study had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.