Post-herpetic encephalitis cerebral abscess: Viral reactivation or latency site within central nervous system?

Curr Res Transl Med. 2021 Jul;69(3):103297. doi: 10.1016/j.retram.2021.103297. Epub 2021 Jun 15.

Abstract

Herpetic encephalitis results from central nervous system invasion by herpes simplex virus. We report the case of a man who developed a cerebral abscess fifteen months after initial Herpetic encephalitis. Retrospectively, antiviral should not have been associated with antibiotics during abscess episode, as transcriptomic analysis reported no viral reactivation.

Keywords: Cerebral abscess; Herpes simplex virus; Herpetic encephalitis; Viral transcripts.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Abscess*
  • Central Nervous System
  • Encephalitis, Herpes Simplex* / diagnosis
  • Encephalitis, Herpes Simplex* / drug therapy
  • Herpes Simplex*
  • Humans
  • Male
  • Retrospective Studies