Human adjuvant disease following augmentation mammoplasty

Arch Dermatol. 1988 Sep;124(9):1383-6.


Two patients are described in whom a progressive systemic sclerosis-like illness developed several years after silicone augmentation mammoplasty. Both had removal of breast implants, followed by marked-to-complete recovery from clinical abnormalities. This entity is increasingly recognized and has become known as human adjuvant disease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Breast / surgery*
  • Female
  • Humans
  • Middle Aged
  • Prostheses and Implants / adverse effects*
  • Scleroderma, Systemic / etiology*
  • Scleroderma, Systemic / pathology
  • Silicone Elastomers / adverse effects*
  • Surgery, Plastic*


  • Silicone Elastomers