Self-reported parkinsonism features in older autistic adults: A descriptive study

Autism. 2022 Jan;26(1):217-229. doi: 10.1177/13623613211020183. Epub 2021 Jun 21.

Abstract

Autistic adults without a suspected intellectual disability reported several motor features such as having tremors, and stiffness in one's legs which are considered to be part of a complex of motor features called parkinsonism. This so-called parkinsonism was remarkably prevalent in middle-aged and older autistic adults in two independent studies (Dutch study: 50-81 years, 183 males, 113 females, all adulthood diagnoses; the USA study: 50-83 years, 110 females, 109 males, majority adulthood diagnosis). Parkinsonism can be part of the progressive motor disease-Parkinson's disease. Therefore, it is important that future studies, including in-person neurological assessment, determine if (and if so, why) autistic adults who report these motor features are at increased risk for developing Parkinson's disease.

Keywords: autism; medication; old-age; parkinsonism; self-report.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Autism Spectrum Disorder*
  • Autistic Disorder* / epidemiology
  • Female
  • Humans
  • Intellectual Disability*
  • Male
  • Middle Aged
  • Parkinsonian Disorders* / epidemiology
  • Self Report