Current indications for endoscopic submucosal dissection of early gastric cancer

World J Gastrointest Oncol. 2021 Jun 15;13(6):560-573. doi: 10.4251/wjgo.v13.i6.560.


The development of endoscopic treatment technology has further promoted the minimally invasive treatment of early gastric cancer (EGC). Endoscopic treatment has achieved better therapeutic effects in terms of safety and prognosis and is the preferred treatment method for patients who meet the indications for endoscopic treatment. However, the consequent problem is that some patients receiving endoscopic treatment may undergo non-curative resection, and the principle of follow-up management for non-curative resection patients deserves further attention. In addition, there are still debates on how to improve the accuracy of clinical staging, select a reasonable treatment method for patients who meet the expanded indications for endoscopic treatment, manage patients with positive endoscopic surgical margins, conduct research on function-preserving surgery, and manage the treatment of EGC under the current situation in China. Consequently, we aim to review current indications for endoscopic submucosal dissection of EGC in order to better inform treatment options.

Keywords: Early gastric cancer; Endoscopic submucosal dissection indications; Function-preserving surgery; Non-curative resection; Salvage surgery.

Publication types

  • Review