Acute myocarditis after a second dose of the mRNA COVID-19 vaccine: a report of two cases

Joseph Mansour; Ryan G Short; Sanjeev Bhalla; Pamela K Woodard; Amanda Verma; Xavier Robinson; Demetrios A Raptis

doi:10.1016/j.clinimag.2021.06.019

Acute myocarditis after a second dose of the mRNA COVID-19 vaccine: a report of two cases

Clin Imaging. 2021 Oct:78:247-249. doi: 10.1016/j.clinimag.2021.06.019. Epub 2021 Jun 18.

Authors

Joseph Mansour¹, Ryan G Short², Sanjeev Bhalla², Pamela K Woodard², Amanda Verma³, Xavier Robinson², Demetrios A Raptis²

Affiliations

¹ Mallinckrodt Institute of Radiology, Washington University School of Medicine, United States. Electronic address: jmansou@iu.edu.
² Mallinckrodt Institute of Radiology, Washington University School of Medicine, United States.
³ Cardiovascular Division, Washington University School of Medicine, United States.

Abstract

We report two cases of myocarditis, in two young and previously healthy individuals, temporally related to the second dose of the mRNA-COVID-19 vaccine. Both patients developed acute chest pain, changes on electrocardiogram (ECG), and elevated serum troponin within two days of receiving their second dose. Cardiac magnetic resonance (CMR) findings were consistent with acute myocarditis.

Keywords: Acute myocarditis; COVID-19 vaccination; Cardiac magnetic resonance; Myocarditis; mRNA-COVID-19 vaccine.

Publication types

Case Reports

MeSH terms

COVID-19 Vaccines
COVID-19*
Humans
Myocarditis* / diagnostic imaging
RNA, Messenger
SARS-CoV-2

Substances

COVID-19 Vaccines
RNA, Messenger