What's in fake 'Xanax'?: A dosage survey of designer benzodiazepines in counterfeit pharmaceutical tablets

Drug Test Anal. 2022 Mar;14(3):525-530. doi: 10.1002/dta.3119. Epub 2021 Jul 1.

Abstract

The identification of a range of different drugs within counterfeit benzodiazepine tablets has been widely reported; however, limited information is available on the dosage of these products. A rapid dosage survey of 46 counterfeit benzodiazepine tablets from 20 seizures was conducted over a 6-month period between April and September 2020. Existing methods utilised for the determination of benzodiazepines in toxicology specimens were applied to assess the dosage of four benzodiazepines detected across five different counterfeit benzodiazepine presentations. The highest dosage variation was observed for etizolam with a range of 0.7-8.3 mg per tablet. This report demonstrates the variability in drug content and dosage that can occur between visually similar counterfeit tablets, even when co-packaged within the same seizure, highlighting the potential public harm posed by these counterfeit medications.

Keywords: Etizolam; NPS; benzodiazepines; counterfeit; dosage.

MeSH terms

  • Alprazolam*
  • Benzodiazepines
  • Counterfeit Drugs*
  • Tablets

Substances

  • Counterfeit Drugs
  • Tablets
  • Benzodiazepines
  • Alprazolam