Potential immune response to breast implants after immunization with COVID-19 vaccines

Breast. 2021 Oct:59:76-78. doi: 10.1016/j.breast.2021.06.002. Epub 2021 Jun 18.


Besides reports of alarming potential side effects after COVID-19 vaccinations there have been rare observations of rather benign reactions to foreign materials such as cosmetic hyaluronic acid filler injections after a COVID-19 immunization. Likewise to dermal fillers any foreign material may cause a reaction when the immune system is triggered. In the recent weeks we observed four noteworthy potential reactions in association with breast implants between one and three days after COVID-19 vaccinations. We release these information at the earliest to educate colleagues and draw attention to possible reactions between the COVID-19 vaccines and foreign bodies such as breast implants.

Keywords: Breast augmentation; Breast implant; Breast reconstruction; COVID-19; Immune response; Vaccination.

MeSH terms

  • Aged
  • Breast Implants / adverse effects*
  • Breast Neoplasms
  • COVID-19 / prevention & control*
  • COVID-19 Vaccines / administration & dosage*
  • COVID-19 Vaccines / adverse effects
  • Dermal Fillers* / administration & dosage
  • Female
  • Fibrosis
  • Humans
  • Immunity*
  • Middle Aged
  • Pain
  • SARS-CoV-2
  • Vaccination / adverse effects


  • COVID-19 Vaccines
  • Dermal Fillers