Predictors of the Pressor Response to the Norepinephrine Transporter Inhibitor, Atomoxetine, in Neurogenic Orthostatic Hypotension

Hypertension. 2021 Aug;78(2):525-531. doi: 10.1161/HYPERTENSIONAHA.119.14483. Epub 2021 Jun 28.

Abstract

[Figure: see text].

Keywords: Parkinson disease; biomarker; hypotension, orthostatic; norepinephrine; pure autonomic failure.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenergic Uptake Inhibitors / pharmacology*
  • Aged
  • Atomoxetine Hydrochloride / pharmacology*
  • Blood Pressure / drug effects*
  • Female
  • Humans
  • Hypotension, Orthostatic / blood
  • Hypotension, Orthostatic / physiopathology*
  • Male
  • Middle Aged
  • Multiple System Atrophy / blood
  • Multiple System Atrophy / physiopathology*
  • Norepinephrine / blood
  • Parkinson Disease / blood
  • Parkinson Disease / physiopathology*
  • Pure Autonomic Failure / blood
  • Pure Autonomic Failure / physiopathology*
  • Retrospective Studies

Substances

  • Adrenergic Uptake Inhibitors
  • Atomoxetine Hydrochloride
  • Norepinephrine