Extremely Advanced Breast Cancer Presentation: Possible Effect of Coronavirus Pandemic Anxiety

In Vivo. 2021 Jul-Aug;35(4):2331-2335. doi: 10.21873/invivo.12508.


Background/aim: Corona virus infection dramatically spread worldwide during 2020 and extraordinary restrictions have been implemented in order to reduce viral transmission. These measures compelled a complete restructuring of the health system, including temporary cancer screening suspension and a significant slow-down in cancer diagnoses and treatments.

Case report: We report five cases of extremely advanced breast cancer referred to our Department amid the COVID-19 pandemic. These patients exhibited a poor prognosis or worse quality of life due to their oncological disease.

Conclusion: In our opinion, both the slow-down of diagnosis and treatment of oncological disease and anxiety over COVID-19 influenced this presentation. Moreover, other patients were unable to receive palliative care. Hopefully, these cases will not develop into extremely advanced-stage disease, and we will be able to provide at least the necessary palliative care.

Keywords: COVID-19; COVID-19 pandemic; advanced breast cancer; breast cancer clinical presentation; lockdown..

Publication types

  • Case Reports

MeSH terms

  • Anxiety / diagnosis
  • Anxiety / epidemiology
  • Breast Neoplasms* / diagnosis
  • Breast Neoplasms* / epidemiology
  • COVID-19*
  • Female
  • Humans
  • Pandemics
  • Quality of Life
  • SARS-CoV-2