Clinical syndromes of myasthenia in infancy and childhood. A review

Arch Neurol. 1978 Feb;35(2):97-103. doi: 10.1001/archneur.1978.00500260035009.

Abstract

Ten clinical syndromes of defective neuromuscular transmission in infancy and childhood are reviewed. Autoimmune, genetic, infectious, and pharmacologic mechanisms have been implicated. These disorders manifest themselves in a variety of ways including severe respiratory insufficiency. Prompt diagnosis and treatment may be lifesaving.

Publication types

  • Review

MeSH terms

  • Acetylcholinesterase / deficiency
  • Age Factors
  • Anti-Bacterial Agents / adverse effects
  • Botulism / complications
  • Brain Neoplasms / complications
  • Child
  • Child, Preschool
  • Cholinesterase Inhibitors / therapeutic use
  • Collagen Diseases / complications
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Newborn, Diseases / physiopathology
  • Male
  • Myasthenia Gravis* / physiopathology
  • Myasthenia Gravis* / therapy
  • Pregnancy
  • Sex Factors
  • Syndrome

Substances

  • Anti-Bacterial Agents
  • Cholinesterase Inhibitors
  • Acetylcholinesterase