Abstract
Ten clinical syndromes of defective neuromuscular transmission in infancy and childhood are reviewed. Autoimmune, genetic, infectious, and pharmacologic mechanisms have been implicated. These disorders manifest themselves in a variety of ways including severe respiratory insufficiency. Prompt diagnosis and treatment may be lifesaving.
MeSH terms
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Acetylcholinesterase / deficiency
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Age Factors
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Anti-Bacterial Agents / adverse effects
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Botulism / complications
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Brain Neoplasms / complications
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Child
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Child, Preschool
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Cholinesterase Inhibitors / therapeutic use
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Collagen Diseases / complications
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Female
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Humans
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Infant
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Infant, Newborn
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Infant, Newborn, Diseases / physiopathology
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Male
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Myasthenia Gravis* / physiopathology
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Myasthenia Gravis* / therapy
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Pregnancy
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Sex Factors
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Syndrome
Substances
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Anti-Bacterial Agents
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Cholinesterase Inhibitors
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Acetylcholinesterase