Rat-bite fever: Taking the bite out of a textbook case of Streptobacillus moniliformis blood stream infection

IDCases. 2021 Jun 16:25:e01199. doi: 10.1016/j.idcr.2021.e01199. eCollection 2021.


Increasing popularity of rats as domestic pets and continued use of rodents in scientific laboratories has contributed to a notable increase in reported cases of rat-bite fever caused by Streptobacillus moniliformis in the United States. S. moniliformis is a gram-negative filamentous bacterium that is a commensal bacterium found in the nasopharyngeal tract of rats. This is a case of a young male developing rat-bite fever bacteremia without a known bite from a rat, but with incidental contact with oral secretions. The patient developed significant debilitating symptoms including migratory polymyalgias and demonstrated complete recovery after treatment with ceftriaxone.

Keywords: Rat-bite fever; Rats; Streptobacillus moniliformis.

Publication types

  • Case Reports