Extended JAZ degron sequence for plant hormone binding in jasmonate co-receptor of tomato SlCOI1-SlJAZ

Sci Rep. 2021 Jun 30;11(1):13612. doi: 10.1038/s41598-021-93067-1.


(+)-7-iso-Jasmonoyl-L-isoleucine (JA-Ile) is a lipid-derived phytohormone implicated in plant development, reproduction, and defense in response to pathogens and herbivorous insects. All these effects are instigated by the perception of JA-Ile by the COI1-JAZ co-receptor in the plant body, which in Arabidopsis thaliana is profoundly influenced by the short JAZ degron sequence (V/L)P(Q/I)AR(R/K) of the JAZ protein. Here, we report that SlJAZ-SlCOI1, the COI1-JAZ co-receptor found in the tomato plant, relies on the extended JAZ degron sequence (V/L)P(Q/I)AR(R/K)XSLX instead of the canonical JAZ degron. This finding illuminates our understanding of the mechanism of ligand perception by JA-Ile in this plant, and will inform both efforts to improve it by genetic modification of the SlCOI1-SlJAZ co-receptor, and the development of the synthetic agonists/antagonists.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Arabidopsis / genetics
  • Arabidopsis / metabolism
  • Cyclopentanes* / metabolism
  • Isoleucine / analogs & derivatives*
  • Isoleucine / genetics
  • Isoleucine / metabolism
  • Plant Growth Regulators / genetics
  • Plant Growth Regulators / metabolism
  • Plant Proteins* / genetics
  • Plant Proteins* / metabolism
  • Repressor Proteins* / genetics
  • Repressor Proteins* / metabolism
  • Solanum lycopersicum* / genetics
  • Solanum lycopersicum* / metabolism


  • Cyclopentanes
  • Plant Growth Regulators
  • Plant Proteins
  • Repressor Proteins
  • jasmonoyl-isoleucine
  • Isoleucine