Factors associated with missing strings and expulsion after postplacental insertion of copper T380A intrauterine devices

Int J Gynaecol Obstet. 2022 Apr;157(1):67-75. doi: 10.1002/ijgo.13806. Epub 2021 Jul 27.

Abstract

Objective: To identify clinical and demographic factors associated with missing strings and expulsion after postplacental insertion of copper T380A intrauterine devices (TCu380A IUD).

Methods: This is a secondary analysis of an implementation study. We followed participants who had a postplacental TCu380A IUD insertion, at two postpartum visits: 45-90 days (visit 1) and 6-9 months (visit 2). We used multiple log-binomial regression models to evaluate the demographic and clinical variables associated with missing strings and with IUD expulsion.

Results: We included 705 participants who had a postplacental IUD insertion. We observed missing strings in 275 (47.9%) participants at visit 1, and in 127 (34.2%) participants at visit 2. We identified 61 expulsions (8.9%) by visit 2. In the multiple regression models, only the delivery type was associated with missing strings and expulsion. Compared with vaginal delivery, cesarean delivery increased the risk of missing strings (adjusted relative risk [aRR] 6.21; 95% confidence interval [CI] 4.29-8.99) but reduced the risk of IUD expulsion (aRR 0.24; 95% CI 0.13-0.43).

Conclusion: The delivery mode was the only factor associated with missing strings and expulsion after postplacental IUD insertion. Cesarean section was associated with an increased risk of missing strings but decreased risk of expulsion after postplacental TCu380A IUD insertion.

Keywords: cesarean delivery; copper intrauterine device; expulsion; missing strings; postplacental insertion; vaginal delivery.

MeSH terms

  • Cesarean Section
  • Copper
  • Female
  • Humans
  • Intrauterine Device Expulsion / etiology
  • Intrauterine Devices*
  • Intrauterine Devices, Copper* / adverse effects
  • Postpartum Period
  • Pregnancy
  • Time Factors

Substances

  • Copper