Quality of Life in Hidradenitis Suppurativa: An Update

Int J Environ Res Public Health. 2021 Jun 6;18(11):6131. doi: 10.3390/ijerph18116131.


Knowledge on hidradenitis suppurativa/acne inversa (HS) is rapidly increasing. HS has a profound impact on patients and their family life. Several factors, such as comorbidities, unemployment and HS severity, make this impact even more severe. The most widely used instrument to measure this impact is the dermatology-specific DLQI. We also identified six HS-specific health-related quality of life (HRQoL) instruments. Of them, HIDRAdisk, HSIA, HiSQOL and HSQoL-24 are better validated but there is still lack of experience of its use. Several treatment methods showed positive effect on patients' HRQoL. Surgery remains a method with a substantial positive effect on HRQoL. Several studies confirming a positive effect of adalimumab on the HRQoL of patients with HS were published during the last three years. Data on the influence of several other biologics on HRQoL of HS patients are controversial or based on studies with a small number of patients.

Keywords: biologics; hidradenitis suppurativa; impact; quality of life; surgery; treatment.

Publication types

  • Review

MeSH terms

  • Biological Products*
  • Hidradenitis Suppurativa* / epidemiology
  • Humans
  • Quality of Life
  • Research Design
  • Severity of Illness Index
  • Unemployment


  • Biological Products