Central sparing in annular macular degeneration

Am J Ophthalmol. 1988 Sep 15;106(3):286-92. doi: 10.1016/0002-9394(88)90363-7.

Abstract

Using fluorescein angiography and monochromatic photography, we measured the size of the central sparing in 45 patients with annular maculopathy (mean +/- S.D., 0.34 +/- 0.15 disk diameter; range, 0.10 to 0.65 disk diameter) and compared it with the size of macular yellow pigment in 40 subjects (mean +/- S.D., 0.31 +/- 0.12 disk diameter; range, 0.1 to 0.5 disk diameter). The close approximation of these values suggested that macular yellow pigment contributed to the annular pattern through a photoprotective mechanism.

MeSH terms

  • Fluorescein Angiography
  • Fovea Centralis / metabolism
  • Fovea Centralis / pathology*
  • Fundus Oculi
  • Humans
  • Macula Lutea / pathology*
  • Macular Degeneration / metabolism
  • Macular Degeneration / pathology*
  • Models, Theoretical
  • Retinal Pigments / metabolism

Substances

  • Retinal Pigments