Panuveitis following Vaccination for COVID-19

Ocul Immunol Inflamm. 2021 May 19;29(4):741-742. doi: 10.1080/09273948.2021.1949478. Epub 2021 Jul 2.


Background: COVID-19 vaccination has been accompanied by reports of inflammatory events. This report details a case of panuveitis following vaccination for COVID-19 Case.Description: A 43 year old female developed panuveitis with decreased vision three days after her second dose of Pfizer-Biontech mRNA vaccine. The choroid was significantly thickened and there was anterior chamber and vitreous inflammation. Shortly after onset of ocular symptoms she was also found have an asymptomatic COVID-19 infection. Treatment with oral and topical corticosteroids resulted in improvement in the panuveitis, with a mild recurrence after the initial attempt to taper these drugs.Conclusion: This report demonstrates a likely occurrence of vaccine-related panuveitis secondary to the Pfizer-Biotech mRNA vaccine for COVID-19.

Keywords: COVID-19; Panuveitis; choroidal thickening; mRNA vaccine; vaccination.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anterior Chamber / diagnostic imaging*
  • COVID-19 / epidemiology
  • COVID-19 / prevention & control*
  • COVID-19 Vaccines / adverse effects*
  • Female
  • Humans
  • Panuveitis / diagnosis
  • Panuveitis / etiology*
  • SARS-CoV-2 / immunology*
  • Tomography, Optical Coherence / methods
  • Vaccination / adverse effects*


  • COVID-19 Vaccines