Epilepsy Surgery: Monitoring and Novel Surgical Techniques

Neurol Clin. 2021 Aug;39(3):723-742. doi: 10.1016/j.ncl.2021.04.001. Epub 2021 Jun 9.

Abstract

Drug-resistant epilepsy warrants referral to an epilepsy surgery center for consideration of alternative treatments including epilepsy surgery. Advances in technology now allow for minimally invasive neurophysiologic monitoring and surgical interventions, approaches that are attractive to families because large craniotomies and associated morbidity are avoided. This work reviews the presurgical evaluation process and discusses the use of invasive stereo-electroencephalography monitoring to localize seizure onset zones. Minimally invasive surgical techniques are described for the treatment of focal and generalized epilepsies. These approaches have expanded our capacity to palliate and cure epilepsy in the pediatric population.

Keywords: Drug-resistant epilepsy; Laser interstitial thermal therapy; Minimally invasive surgery; Stereo-electroencephalography.

Publication types

  • Review

MeSH terms

  • Child
  • Drug Resistant Epilepsy* / diagnosis
  • Drug Resistant Epilepsy* / surgery
  • Electroencephalography
  • Epilepsy* / diagnosis
  • Epilepsy* / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Seizures
  • Treatment Outcome