Epilepsy: Epileptic Syndromes and Treatment

Abstract

Epilepsy can now be diagnosed even in the presence of one unprovoked seizure or if the diagnosis of an epilepsy syndrome can be made. Epilepsy syndromes represent a specific set of seizure types and electroencephalographic and imaging features that tend to have age-dependent features, triggers, and prognosis. Epilepsy syndromes are the third and final level of epilepsy diagnosis, after classification of seizure and epilepsy types. Some epilepsy syndromes are self-limiting and pharmacoresponsive and others are pharmacoresistant and associated with poor developmental outcomes (epileptic and developmental encephalopathy). Features and management of 7 common age-dependent pediatric epilepsy syndromes are described.

Keywords: Childhood absence epilepsy; Childhood epilepsy with centrotemporal spikes; Dravet syndrome; Epilepsy; Epilepsy syndrome; Infantile spasms; Juvenile myoclonic epilepsy; Lennox-Gastaut syndrome.