Unique karyotypic abnormalities in a squamous cell carcinoma of the larynx

Cancer Genet Cytogenet. 1988 Jan;30(1):177-9. doi: 10.1016/0165-4608(88)90109-4.

Abstract

We have cytogenetically examined short-term cultures from a squamous cell carcinoma of the larynx, a type of carcinoma in which chromosome aberrations have hitherto not been reported. The tumor karyotype was 46,XY,inv(2)(p22q24),t(9;13)(q34;q12),t(11;18)(q23;q21). None of these abnormalities have been described in carcinomas before.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Carcinoma, Squamous Cell / genetics*
  • Chromosome Aberrations*
  • Chromosome Banding
  • Genetic Markers
  • Humans
  • Karyotyping
  • Laryngeal Neoplasms / genetics*
  • Male

Substances

  • Genetic Markers