The Tuberculosis Drug Accelerator at year 10: what have we learned?
Nat Med
.
2021 Aug;27(8):1333-1337.
doi: 10.1038/s41591-021-01442-2.
Authors
Bree B Aldridge
1
,
David Barros-Aguirre
2
,
Clifton E Barry 3rd
3
,
Robert H Bates
2
,
Steven J Berthel
4
,
Helena I Boshoff
3
,
Kelly Chibale
5
,
Xin-Jie Chu
6
,
Christopher B Cooper
7
,
Véronique Dartois
8
,
Ken Duncan
9
,
Nader Fotouhi
7
,
Fabian Gusovsky
10
,
Philip A Hipskind
11
,
Dale J Kempf
12
,
Joël Lelièvre
2
,
Anne J Lenaerts
13
,
Case W McNamara
14
,
Valerie Mizrahi
5
,
Carl Nathan
15
,
David B Olsen
16
,
Tanya Parish
17
,
H Michael Petrassi
14
,
Alexander Pym
18
,
Kyu Y Rhee
19
,
Gregory T Robertson
13
,
Jeremy Michael Rock
20
,
Eric J Rubin
21
,
Betsy Russell
22
,
David G Russell
23
,
James C Sacchettini
24
,
Dirk Schnappinger
19
,
Michael Schrimpf
12
,
Anna M Upton
25
,
Peter Warner
9
,
Paul Graham Wyatt
26
,
Ying Yuan
6
Affiliations
1
Tufts University, Boston, MA, USA.
2
GlaxoSmithKline, Tres Cantos, Spain.
3
National Institutes of Health, Bethesda, MD, USA.
4
Panorama Global, Seattle, WA, USA.
5
University of Cape Town, Cape Town, South Africa.
6
Global Health Drug Discovery Institute, Beijing, China.
7
Global Alliance for TB Drug Development, New York, NY, USA.
8
Hackensack Meridian Health Center for Discovery & Innovation, Nutley, NJ, USA.
9
Bill & Melinda Gates Foundation, Seattle, WA, USA.
10
Eisai, Andover, MA, USA.
11
Lgenia, Fortville, IN, USA.
12
AbbVie, North Chicago, IL, USA.
13
Colorado State University, Fort Collins, CO, USA.
14
Calibr, a division of the Scripps Research Institute, La Jolla, CA, USA.
15
Weill Cornell Medicine, New York, NY, USA. cnathan@med.cornell.edu.
16
Merck & Co., West Point, PA, USA.
17
Seattle Children's Research Institute, Seattle, WA, USA.
18
Janssen-Cilag, Buckinghamshire, UK.
19
Weill Cornell Medicine, New York, NY, USA.
20
The Rockefeller University, New York, NY, USA.
21
Harvard T.H. Chan School of Public Health, Boston, MA, USA.
22
Bill & Melinda Gates Medical Research Institute, Boston, MA, USA.
23
Cornell University, Ithaca, NY, USA.
24
Texas A&M University, College Station, TX, USA.
25
Evotec, Lyon, France.
26
Drug Discovery Unit, University of Dundee, Dundee, Scotland.
PMID:
34226736
DOI:
10.1038/s41591-021-01442-2
No abstract available
MeSH terms
Antitubercular Agents / chemistry
Antitubercular Agents / therapeutic use*
Drug Design*
Humans
Learning
Time Factors
Tuberculosis / drug therapy*
Substances
Antitubercular Agents