Redo fundoplication and early Roux-en-Y diversion for failed fundoplication: a 3-year single-center experience

Surg Endosc. 2022 May;36(5):3094-3099. doi: 10.1007/s00464-021-08610-y. Epub 2021 Jul 6.


Background: Redo fundoplication (RF) and Roux-en-Y diversion (RNY) are both accepted surgical treatments after failed fundoplication. However, due to higher reported morbidity, RNY is more commonly performed only after several surgical failures. In our experience, RNY at an earlier point of the disease progression seems to be related with better outcomes. The aim of this study was to investigate this aspect by comparing the results between RF and RNY performed by a single surgeon over 3 years at our institution.

Methods: A prospectively maintained database was reviewed to identify patients who underwent RF or RNY at our institution between 2016 and 2019 by a single surgeon (author SKM). Patients with previous bariatric surgery were excluded.

Results: Of 43 patients, 28 underwent RF and 15 underwent RNY (mean body mass index 28.6 and 32.7 kg/m2, respectively, p = 0.01). The number of previous antireflux surgeries for the RF and RNY groups was 1 (82% vs 80%, p > 0.99), 2 (18% vs 7%, p = 0.4), and more than 2 (0% vs 13%, p = 0.1). RNY took longer than RF (median, 165 vs 137 min, p = 0.02), but both groups had a median estimated blood loss of 50 ml (p = 0.82). There was no difference in intraoperative complications (25% vs 20% for RF and RYN, respectively, p > 0.99). Postoperative complications were more common in the RF than in the RYN group (21% vs 7%, p = 0.39). Median hospital stay was 3 days for both groups (p = 0.78). At short-term follow-up, the mean quality of life score was similar for the RF and RYN groups (11.5 vs 12.2, p = 0.8).

Conclusions: RNY diversion, if performed by experienced hands and at an earlier point of disease progression, has comparable perioperative morbidity to RF and should be considered as a feasible and safe option for definitive treatment of failed antireflux surgery.

Keywords: Antireflux procedure; Fundoplication; GERD; Gastroesophageal reflux disease; Redo; Roux-en-Y.

MeSH terms

  • Anastomosis, Roux-en-Y / methods
  • Disease Progression
  • Fundoplication / methods
  • Gastroesophageal Reflux* / complications
  • Gastroesophageal Reflux* / surgery
  • Humans
  • Laparoscopy* / methods
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Postoperative Complications / surgery
  • Quality of Life
  • Reoperation / adverse effects
  • Retrospective Studies
  • Treatment Outcome