[Association between age-related macular degeneration and periodontal disease]

J Fr Ophtalmol. 2021 Oct;44(8):1142-1147. doi: 10.1016/j.jfo.2021.01.008. Epub 2021 Jul 8.
[Article in French]


Purpose: To evaluate the association between age-related macular degeneration (AMD) and periodontal disease, two frequent conditions in the elderly, with some risk factors in common.

Methods: Single center, pilot, case-control study performed in a center specialized in the diagnosis and management of AMD. Periodontal status was evaluated in 43 AMD patients and 19 controls. Fundus examination and a complete periodontal examination were performed in all subjects.

Results: AMD patients have a greater percentage of 3-4mm clinical attachment loss compared to controls (47% vs. 38%, [P=0.039]). However, no significant difference was found between the groups with regard to the prevalence of severe periodontitis.

Conclusions: These results suggest an association between AMD and attachment loss characteristic of periodontal disease and support the need for larger prospective studies to elucidate the relationships between these 2 highly prevalent and potentially severe diseases.

Keywords: Age-related macular degeneration; Case-control study; Dégénérescence maculaire (FMeSH); Parodontite (FMeSH); Periodontal disease; Étude cas témoins.

MeSH terms

  • Aged
  • Case-Control Studies
  • Humans
  • Macular Degeneration* / complications
  • Macular Degeneration* / diagnosis
  • Macular Degeneration* / epidemiology
  • Periodontal Diseases* / complications
  • Periodontal Diseases* / diagnosis
  • Periodontal Diseases* / epidemiology
  • Prospective Studies
  • Risk Factors