One year in review 2021: systemic sclerosis

Clin Exp Rheumatol. 2021 Jul-Aug;39 Suppl 131(4):3-12. doi: 10.55563/clinexprheumatol/izadb8. Epub 2021 Jul 1.


Systemic sclerosis is a rare and chronic connective tissue disease with a multifaceted pathogenesis characterised by heterogeneous multi-organ clinical manifestations. Every year, many studies contribute to enrich the knowledge on the pathogenesis, organ involvement and treatment of this complex and severe disease. We herein provide an overview on the most relevant contributions published in the literature in 2020.

Publication types

  • Review

MeSH terms

  • Humans
  • Scleroderma, Systemic* / diagnosis
  • Scleroderma, Systemic* / therapy